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Zhiyang MachineryZhiyang Machinery

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Focus on life, Focus on medicine

The quality of the tablet coating machine is judged from these aspects

Date:2020-02-23 07:32:22
  The tablet coating machine is an instrument designed by Changzhou Zhiyang Mechanical Equipment Co., Ltd. for medical schools, new drug development and pharmaceutical company laboratories. This device can observe tablets, small granule pills, outer coating and film coating The process of making capsule granules and obtaining accurate experimental data can also be used for small batch production of new special drugs. It is an essential equipment for the pharmaceutical industry. All test results obtained on the tablet coater were tested for acceptance of the quality limit. The results show that under the conditions of different process parameters, the color uniformity and scoring clarity of the samples of the tablet coating machine meet the requirements.
  The tablet coating machine can obtain tablets of acceptable quality under all set test conditions. Tablets coated using a batch tablet coater are slightly better in gloss and surface roughness than coated tablets of a continuous tablet coater. Therefore, when comparing the batch coating process to the continuous coating process, the aesthetics and productivity of the tablet are weighed.
  The tablet coating machine has a test that examines the rotation speed and the uniformity of the coating. In the test, it can be seen that the thickness of the tablet bread is greater than the diameter of the tablet, and the diameter of the tablet is greater than the boundary between the two. Considering that it is not easy to observe the selection of the film diameter and surface comparison, it can be seen that increasing the rotation speed and reducing the sliding of the film bed improves the coating more uniformly after the waterfall, but too fast rotation speed will cause increased wear. There are many parameters that affect the speed setting, such as the size and shape of the core, the friability and smoothness of the core, the baffle, the volume, and the drying capacity. The size, shape, and smoothness of the core and the shape of the baffle have an impact on the formation of the waterfall on the film bed. The cores with flat surfaces sometimes stick together to form twins or even twins due to drying. Adding a small radian to the core plane can solve it. The friability of the tablet core is not difficult to understand. If the friability is poor, an excessively fast rotation speed will cause burrs, debris, etc. When the loading amount of the chip core is small, the rotation speed can be improved in order to compensate for the sliding of the film bed. In addition, the drying speed and drying capacity of the coating process also affect the rotation speed. If the drying speed is slow, you can improve the drying time by reducing the spray volume and reducing the rotation speed. Therefore, the rotation speed can be selected to make the film bed the lowest rotation speed.
  The gloss of the tablets coated by the tablet coater is lower than that of the reference tablets, but all meet the acceptance quality limit (AQL). Moreover, the output of coated tablets increased significantly, with a productivity of more than 200 kg / h. If you want to obtain the same tablet output on a 36? Batch tablet coating machine, without considering the loading and unloading, you need to perform at least 4 batch coatings, each batch takes 50 minutes, the total The working time required 3.5 hours, while the continuous tablet coater can be completed in only 1 hour.
  For the drying of the coating process, the tablet coating machine is more important than the temperature, which is also the main source of the difference in the performance of the equipment at home and abroad. It should be noted that the control of the negative pressure formed by the intake and exhaust air is not that the larger the negative pressure is, the better the negative pressure is. If the negative pressure is too large, the air leakage at the feeding door will affect the spray effect.

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